<dd id="zkfju"><track id="zkfju"></track></dd><tbody id="zkfju"></tbody>

    Solutions of Vaccine Process Filtration

    Filtration technology has a wide range of applications in different stages of the vaccine process, such as the gas sterile filtration, the mycoplasma sterile filtration for culture medium, the buffer sterile filtration, the separation of bacteria, and the concentration of protein, polysaccharide or virus particles, dialysis, buffer replacement, final product sterile filtration, etc.


    The vaccine is an autoimmune preparation made of pathogenic microorganisms (such as bacteria, rickettsiae, viruses, etc.) and their metabolites through artificial attenuation, inactivation or genetically modified methods to prevent infectious diseases . Currently, the vaccine family including 7 types as Live Attenuated Vaccine, Whole Inactivated Vaccine, R-Protein Vaccine, Polysaccaride-conjugate Vaccine, mRNA&DNA Vaccine and Live Vectored Vaccines Wait.


    The development of vaccines is divided into three stages:


    The first stage: In 1789, the British doctor Jenner proved that vaccinia can prevent smallpox, calling this technique a vaccination. In the 19th century, Pasteur, the father of vaccines, invented live attenuated vaccines, such as the Sabin attenuated strain polio vaccine, which was of epoch-making significance. The attenuated BCG vaccine developed by Kamet and Gulin. It still used to prevent tuberculosis today.


    The second stage: the advent of recombinant genetic vaccine, for example, using genetic engineering technology to prepare hepatitis B surface antigen as a vaccine for clinical inoculation, the safety is greatly improved, and it is easy to produce and store on a large scale. we use antigen protein technology to bring vaccine research to the molecular level. At present, there are mainly subunit vaccines, peptide vaccines and multiple vaccines.


    The third stage: The emergence of nucleic acid vaccines in the 1990s, including mRNA & DNA vaccines. Nucleic acid vaccines can be quickly designed with low cost, easy operation and stable properties. The nucleic acid vaccine can be stored at room temperature, which improves the vaccination rate.


    In the 21st century, a variety of new vaccines include: therapeutic vaccines, pentavalent rotavirus, viroid (such as HPV) and polyvalent vaccines and other blockbusters are on the market. The global vaccine sales in 2019 reached about 55 billion US dollars. Sales in China reached about 30 billion RMB.


    Flow Diagram of Bioprocess

    Vaccine-cbt.jpg



    ①-Media Filtration

    Bioburden Reduction and Particle Control

    Greclary CHV -Glass Fiber

    Excesal CHE -PP

    Excesal CHC -PP
    Excesal CHT -PP

    Safetect PME -PES

    Purcise PLE -Double Layer PES

    Purcise PAF -PES

    Corevital PMD -PVDF



    Sterilizing-grade Filter Series

    Purcise SLE -Double Layer PES

    Corevital SAF -Double Layer PES

    Corevital SMD -PVDF



    Mycoplasma Removal Filter Series

    Purcise MLE -Double Layer PES


    ②-Gas Filtration Filter Series

    Safesure AFM -Hydrophobic PTFE

    Aegivast ACE -Hydrophobic PTFE

    Corevital APB -Hydrophobic PVDF


    ③-Clarification Filtration

    Roheap CSD

    Greclary CHV -Glass Fiber

    Excesal CHE -PP

    Excesal CHC -PP
    Excesal CHT -PP

    Safetect PME -PES

    Purcise PLE -Double Layer PES

    Purcise PAF -PES

    Corevital PMD -PVDF

     

     

    ④-Column / TFF Protection

    Safetect PME -PES

    Purcise PLE -Double Layer PES

    Purcise PAF -PES

    Corevital PMD -PVDF

    Purcise SLE -Double Layer PES

    Corevital SAF -Double Layer PES

    Corevital SMD -PVDF


     

    ⑤-Cassettes

    Consieve?UET TFF ( Cassettes /Stainless Holder /System )

     


    ⑦-Sterile Filtration

    Purcise SLE -Double Layer PES

    Corevital SAF -Double Layer PES

    Corevital SMD -PVDF








    免费一级无码婬片AA片高潮喷水,91久久综合亚洲鲁鲁五月天,97人妻人人揉人人躁人人